The ABOUT Network has enrolled 10,500 participants. Here is a snapshot of the ABOUT members who have provided consent and completed the baseline questionnaire to date:
Nearly 56% of participants have been diagnosed with breast cancer. About five percent of women have been diagnosed with ovarian cancer, and over seven percent of men have been diagnosed with prostate cancer. Melanoma and pancreatic cancers are also hereditary cancers that have been associated with genetic mutations, and participants reported diagnoses of other non-hereditary cancers, with the most common being skin cancer.
Most of the participants in ABOUT have had genetic testing. Overall, 26% of enrolled participants tested positive for a mutation, with the majority having a BRCA 1 or BRCA 2 mutation.
The majority of participants have been diagnosed with cancer at least once. Ten percent had more than one cancer diagnosis and 34% have never been diagnosed with cancer.